Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in … LaMICtal XR (lamoTRIgine)." Some of the dosage forms listed on this page may not apply to the brand name Lamictal. There have been case reports of breastfed infants with breathing problems and anemia (low red blood cell counts). Medicines that interact with Lamictal may either decrease its effect, affect how … It's usual to take lamotrigine once or twice a day. In a prospectively followed cohort of patients 2 to 16 years old (n=1983), 1 rash-related death occurred in a patient with epilepsy taking this drug as adjunctive therapy. I've been on Lamictal since I. I have no words of wisdom. years. Lamotrigine is used alone or together with other medicines to help control certain types of seizures (eg, partial seizures, tonic-clonic seizures, or Lennox-Gastaut syndrome) in the treatment of epilepsy. continuous, uncontrolled back and forth or rolling eye movements See below for a comprehensive list of adverse effects. Available for Android and iOS devices. You may report side effects to the FDA at 1-800-FDA-1088. Lamotrigine (Lamictal) is an inexpensive drug used to control seizures in adults and children with epilepsy and Lennox-Gastaut syndrome.This drug is slightly more popular than comparable drugs. Check with your doctor immediately if any of the following side effects occur: Get emergency help immediately if any of the following symptoms of overdose occur: Some side effects may occur that usually do not need medical attention. Call your doctor for medical advice about side effects. DESCRIPTION. Esfahani FE, Dasheiff RM "Anemia associated with lamotrigine." Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Side Effects. Copyright © 2021 IBM Watson Health. Lamictal side effects. Bipolar Disorder: In the controlled clinical trials, there was no increase in the incidence, type, or severity of adverse reactions following abrupt termination of LAMICTAL. Mueller TH, Beeber AR "Delirium From Valproic Acid With Lamotrigine." 4. Hillemacher T, Bleich S, Kornhuber J, Frieling H "Hair loss as a side effect of lamotrigine treatment." Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Ann Pharmacother 31 (1997): 720-3, 6. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to lamotrigine: oral tablet, oral tablet disintegrating, oral tablet dispersible, oral tablet extended release, The more commonly reported adverse reactions have included dizziness, headache, diplopia, ataxia, nausea, blurred vision, somnolence, and rash. I've been on Lamictal (125 mg twice a day) for 5? Applies to lamotrigine: oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended releaseAlong with its needed effects, lamotrigine (the active ingredient contained in pain or discomfort in the arms, jaw, back, or neck, swelling of the face, fingers, feet, or lower legs, continuous, uncontrolled back and forth or rolling eye movements, Blistering, peeling, or loosening of the skin, sores, ulcers, or white spots on the lips or in the mouth, swelling of the face, mouth, hands, or feet, pains in the stomach or side, possibly radiating to the back, persistent bleeding or oozing from puncture sites, mouth, or nose, continuous, uncontrolled back and forth or rolling eye movements (severe). The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a … Moeller KE, Wei L, Jewell AD, Carver LA "Acute hepatotoxicity associated with lamotrigine." Br J Clin Pharmacol 60 (2005): 666-7, 18. Chaffin JJ, Davis SM "Suspected lamotrigine-induced toxic epidermal necrolysis." Lamotrigine's chemical name is 3,5-diamino-6-(2,3-dichlorophenyl)-as-triazine, its molecular formula is C 9 H 7 N 5 Cl 2, and its molecular weight is 256.09.Lamotrigine is a white to pale cream-colored powder and has a pKa of 5.7. Am J Psychiatry 163 (2006): 1199-201, 21. Discontinuation of LAMICTAL should involve a step-wise reduction of dose over at least 2 weeks (approximately 50% per week) unless safety concerns re… Lamictal (Lamotrigine Chewable Dispersible Tablets), Drug Safety Communication: Lamictal (lamotrigine) - Studies Show Increased Risk of Heart Rhythm Problems in Patients with Heart Disease, pain or discomfort in the arms, jaw, back, or neck, swelling of the face, fingers, feet, or lower legs, continuous, uncontrolled back and forth or rolling eye movements, Blistering, peeling, or loosening of the skin, sores, ulcers, or white spots on the lips or in the mouth, swelling of the face, mouth, hands, or feet, pains in the stomach or side, possibly radiating to the back, persistent bleeding or oozing from puncture sites, mouth, or nose, continuous, uncontrolled back and forth or rolling eye movements (severe). In pediatric patients who used valproate concomitantly for epilepsy, 1.2% (6 of 482) experienced a serious rash (placebo=0.6%). https://reference.medscape.com/drug/lamictal-lamotrigine-343012 The rate of serious rash is greater in pediatric patients than in adults. Glaxo Wellcome, Research Triangle Park, NC. Cerner Multum, Inc. "UK Summary of Product Characteristics." Check with your doctor immediately if any of the following side effects occur while taking lamotrigine: Get emergency help immediately if any of the following symptoms of overdose occur while taking lamotrigine: Some side effects of lamotrigine may occur that usually do not need medical attention. Schwartz R, Avello E, Palisson F "Lamotrigine-induced toxic epidermal necrolysis treated with intravenous immunoglobulin and amniotic membranes." Boot B "Recurrent lamotrigine-induced aseptic meningitis." Neurology 49 (1997): 306-7, 24. This effect can greatly increase your chances of side effects from Lamictal. Other side effects of Lamictal include: Very serious skin reactions are more likely to occur if your body gets exposed to too much of the medication too quickly. Lamictal (lamotrigine)." [Ref], Very common (10% or more): Diplopia (28%), blurred vision (16%), Common (1% to 10%): Vision abnormality, nystagmus, photosensitivity, amblyopia, Uncommon (0.1% to 1%): Abnormality of accommodation, conjunctivitis, dry eyes, photophobia, Rare (less than 0.1%): Lacrimation disorder, oscillopsia, ptosis, strabismus, uveitis, visual field defect[Ref], Very common (10% or more): Vomiting (20%), nausea (19%), diarrhea (10%), Common (1% to 10%): Abdominal pain, vomiting, dyspepsia, constipation, anorexia, dry mouth, rectal hemorrhage, peptic ulcer, flatulence, Uncommon (0.1% to 1%): Dysphagia, eructation, gastritis, gingivitis, increased appetite, increased salivation, mouth ulceration, Rare (less than 0.1%): Gastrointestinal hemorrhage, glossitis, gum hemorrhage, gum hyperplasia, hematemesis, hemorrhagic colitis, melena, stomach ulcer, stomatitis, tongue edema, Very rare (less than 0.01%): Pancreatitis, esophagitis[Ref], Very common (10% or more): Rhinitis (14%), Common (1% to 10%): Pharyngitis, increased cough, epistaxis, dyspnea, bronchitis, sinusitis, bronchospasm, Rare (less than 0.1%): Hiccup, hyperventilation. Common side effects include rash among females and rash among males. Some occur in the initial few days of treatment, but most typically develop within the first two to eight weeks. These side effects may go away during treatment as your body adjusts to the medicine. Ouellet G, Tremblay L, Marleau D "Fulminant hepatitis induced by lamotrigine." Lamictal Side Effects (List of Potential Reactions) Included below is a comprehensive list of side effects that might occur as a result of Lamictal (lamotrigine) treatment. Lamotrigine is used alone or with other medications to prevent and control seizures.It may also be used to help prevent the extreme mood swings of bipolar disorder in adults.Lamotrigine … Lamotrigine oral tablet is a prescription medication used to … gabapentin, fluoxetine, clonazepam, quetiapine, lamotrigine, Abilify, diazepam, Prozac, topiramate, Seroquel. Additionally, the risk did not vary substantially by age. In the clinical development program in adults with bipolar disorder, 2 patients experienced seizures shortly after abrupt withdrawal of LAMICTAL. Data sources include IBM Watson Micromedex (updated 3 May 2021), Cerner Multum™ (updated 4 May 2021), ASHP (updated 3 May 2021) and others. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. 2. One side effect of taking lamotrigine (Lamictal) is a rash, which may turn serious. 1. The median treatment duration was 12 weeks. In adults, 1% of patients of patients receiving this drug in combination with valproate (n=584) experienced a rash (placebo=0.16%). U.S Food & Drug Administration "FDA Drug Safety Communication: FDA warns of serious immune system reaction with seizure and mental health medicine lamotrigine (Lamictal) Available from: URL: https://www.fda.gov/Drugs/DrugSafety/ucm605470.htm?utm_campaign=New%20FDA%20Drug%20Safety%20Comm" ([2018, Apr 25]): 23. And that is just one of the many side effects of this medication. Learn how to recognize it, treat it, and when to get emergency help. Get emergency medical help if you have signs of an allergic reaction to Lamictal (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or … Clin Neuropharmacol 12 (1989): 312-21, 12. Schedule your appointment now for safe in-person care. Learn about side effects, warnings, dosage, and more for lamotrigine oral tablet. If you notice any other effects, check with your healthcare professional. Blood problems and acute organ failure: Lamictal can lead to potentially life-threatening blood and organ disorders.Liver failure, blood clots, muscle breakdown, and blood abnormalities like anemia may be possible. Although not all of these side effects may occur, if they do occur they may need medical attention. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer — Mayo Clinic Health Letter, Time running out - 40% off Online Mayo Clinic Diet ends soon. Verma A, Miller P, Carwile ST, Husain AM, Radtke "Lamotrigine-induced blepharospam." Cases of life-threatening serious rashes, including Stevens-Johnson syndrome and toxic epidermal necrolysis, or rash-related death have been caused by lamotrigine. Essentially, Lamictal is a mood stabilizer medication that works by decreasing abnormal activity exhibited in the brain. Am J Psychiatry 161 (2004): 1128-1129, 16. Saravanan N, Musibay Otaiku O, Namushi Namushi R "Interstitial pneumonitis during lamotrigine therapy." It is also thought to inhibit the release of glutamate at various areas throughout the … Lancet 348 (1996): 1041, 7. Dosage for lamotrigine will typically be 25mg daily for the first two weeks. Common Side Effects of Lamictal . Am J Psychiatry 163 (2006): 749-50, 15. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Although not all of these side effects may occur, if they do occur they may need medical attention. This content does not have an Arabic version. Drug information provided by: IBM Micromedex US Brand Name. LaMICtal; LaMICtal CD; LaMICtal XR; Descriptions. Am J Psychiatry 165 (2008): 539-40. Margolese HC, Beauclair L, Szkrumelak N, Chouinard G "Hypomania Induced by Adjunctive Lamotrigine." Mayo Clinic does not endorse companies or products. Australian prescription products guide online. These side effects may go away during treatment as your body adjusts to the medicine. You may report them to the FDA. This content does not have an English version. In a prospectively followed cohort of pediatric patients 2 to 17 years old, the incidence of serious rash was approximately 0.3% to 0.8%. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Symptoms have been reported within 8 to 24 days. If you are taking lamotrigine how long does it take to get out of your system? Submitted by JunNg on Mon, 2019-01-14 17:43. Side effects are reported by people who take Lamictal. Additional factors that may increase the risk of rash include: (1) coadministration with valproate; (2) exceeding recommended initial dose of lamotrigine; or (3) exceeding recommended dose escalation for lamotrigine. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Common side effects of Lamictal include dizziness, drowsiness, headache, double vision, blurred vision, nausea, vomiting, and rash. The phase IV clinical study is created by eHealthMe based on 65,440 reports from the FDA, and is updated regularly. "Product Information. I also take 40 mg Prozac per day. While this exceeds the expected rate in healthy populations, it is within the range for patients with epilepsy. Other side effects include: infection, dyspepsia, abnormal gait, constipation, and drowsiness. Along with its needed effects, lamotrigine (the active ingredient contained in Lamictal) may cause some unwanted effects. ([2006]): 5. Am J Health Syst Pharm 64 (2007): 273-275, 10. O 0. Rare/serious side effects A serious, life-threatening skin rash (also known as Stevens–Johnson Syndrome) may occur with the use of lamotrigine. Benign rashes are also caused by lamotrigine; however, it is not possible to predict which rashes will prove to be serious or life threatening. Applies to lamotrigine: oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release, Oral route (Tablet; Tablet, Chewable; Tablet, Disintegrating; Tablet, Extended Release). Always follow your doctor’s dosing schedule, as dosing may differ from patient to patient. [Ref], In cases of hemophagocytic lymphohistiocytosis (HLH), patients have presented with signs of systemic inflammation (fever, rash, hepatosplenomegaly, and organ system dysfunction) and blood dyscrasias. Interactions. It works as a sodium channel blocker by inhibiting voltage-sensitive sodium channels. I should note that Deplin intensified the side effects of Lamictal when I drank heavily. But I have been on various seizure medications for 18 years and have lost track of what are side effects of the meds and what are seizure related. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Then the dosage will increase to 50mg for week 3 and week 4. Lamotrigine side effects are relatively harmless when compared to other prescription drug options. All rights reserved. 3. Evidence has show the inclusion of valproate in a multidrug regimen increases the risk of serious, potentially life-threatening rash in both adult and pediatric patients. dizziness You can take it with or without … Lamotrigine should be discontinued at the first sign of rash, unless the rash is clearly not drug related. List Lamictal side effects by likelihood and severity ; Who should not take Lamictal? There were 4 suicides in AED-treated patients (placebo=0). What is Lamictal? Lamictal is a wonder drug. Portions of this document last updated: May 01, 2021. We comply with the HONcode standard for trustworthy health information. Mikati MA, Schachter SC, Schomer DL, Keally M, Osborne-Shafer P, Seaman CA, Sheridan PH, Ashworth M, Kupferberg H, Valakas A, et al "Long-term tolerability, pharmacokinetic and preliminary efficacy study of lamotrigine in patients with resistant partial seizures." Drug information provided by: IBM Micromedex. GlaxoSmithKline, Research Triangle Park, NC. Lamictal (lamotrigine) is an anticonvulsant medication used to treat partial seizures, and tonic-clonic seizures of Lennox-Gastaut syndrome. Uher R, Jones HM "Hallucinations during lamotrigine treatment of bipolar disorder." Mayo Clinic facts about coronavirus disease 2019 (COVID-19), Our COVID-19 patient and visitor guidelines, plus trusted health information, Mayo Clinic Health System patient vaccination updates. Epilepsia 43 (2002): 199-200, 25. Arch Dermatol 144 (2008): 724-6, 20. Description and Brand Names. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Dosage for Lamictal. Lamictal (Lamotrigine) is a drug that is approved for the treatment of epilepsy and bipolar disorder. Possible Side Effects of Lamictal Use and Abuse Typically, if used under direct medical supervision for necessary medicinal purposes, Lamictal can be taken responsibly and safely. Lamictal is a medication prescribed as an anticonvulsant to treat epilepsy and as a mood stabilizer used to treat bipolar disorder. Consult your doctor before taking Lamictal if pregnant or breastfeeding. While the side effects can't compare to what I experienced on Depakote they are still more than just annoying. Epilepsia 50 (2009): 968-9, 11. Aust N Z J Psychiatry 40 (2006): 718, 13. Pooled analyses of 199 placebo-controlled clinical trials of 11 different AEDs (monotherapy or adjunctive therapy) showed twice the risk compared with placebo patients; an estimated incidence of 0.43% (n=27,863) in AED-treated patients compared to 0.24% (n=16,029) in placebo. Let us know how you’re doing! Bowden CL, Calabrese JR, Ketter TA, Sachs GS, White RL, Thompson TR "Impact of lamotrigine and lithium on weight in obese and nonobese patients with bipolar I disorder." That said, it is important to realize that side effects of Lamictal are often subject to significant interindivdiual variation. That said, the drug needs to be titrated up in dosage slowly. Some side effects may not be reported. It’s the brand name for the generic prescription drug lamotrigine. LAMICTAL (lamotrigine), an AED of the phenyltriazine class, is chemically unrelated to existing AEDs. Sachs B, Ronnau AC, Ruzicka T, Gleichmann E, Schuppe HC "Lamotrigine and toxic epidermal necrolysis." Key facts. Pharmaceutical Society of Australia "APPGuide online. Advertising revenue supports our not-for-profit mission. Page RL, ONeil MG, Yarbrough DR, Conradi S "Fatal toxic epidermal necrolysis related to lamotrigine administration." There are some side effects that can occur even when taking it as directed, however. Serious side effects of Lamictal you should report to your doctor include: rash, worsening depression or suicidal thoughts, and ; flu-like symptoms such as body aches or swollen glands. Report side effects from lamotrigine (Lamictal) or other medicines to the FDA MedWatch program, using the information in the “Contact FDA” box at the bottom of this page. Lamictal is generally a well-tolerated medication. Medically reviewed by Drugs.com. I scaled back to one or two beers and was fine. Afterward, the dosage amounts will be at 100mg for week 5 and 200mg for weeks 6 and longer. Hilas O, Charneski L "Lamotrigine-induced Stevens-Johnson syndrome." "Product Information. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Should I avoid certain foods while taking Lamictal? Am J Psychiatry 160 (2003): 183-184, 14. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. When someone takes too much Lamictal, they put themselves at risk of developing a severe, life-threatening skin rash. Avoni P, Contin M, Riva R, Albani F, Liguori R, Baruzzi A "Dysgeusia in epileptic patients treated with lamotrigine: Report of three cases." Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Am J Psychiatry 163 (2006): 1451, 19. Neurology 57 (2001): 1521. Wadelius M, Karlsson T, Wadelius C "Lamotrigine and toxic epidermal necrolysis." In bipolar trials, serious rash occurred in 0.08% of patients receiving this drug as initial monotherapy and 0.13% of patients receiving this drug as adjunctive therapy. Lancet 348 (1996): 1597, 9. 22. Note: This document contains side effect information about lamotrigine. Increased risk of suicidal thoughts and/or behavior: This warning accompanies the whole category of antiepileptic drugs.If you notice any signs of … Lamictal doses depend on the condition being treated and on whether it is used alone or in combination with other antiseizure medications. It’s very important to follow you doctor’s dosing instructions when taking Lamictal. Available from: URL: http://www.appco.com.au/appguide/default.asp." The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a … It is available in brand and generic versions. South Med J 102 (2009): 82-4, 26. The risk of suicidal thoughts or behavior was considered similar among the drugs studied despite their varying mechanisms of action suggesting the risk applies to all AEDs used for any indication. Last updated on Sep 1, 2020. [Ref], Common (1% to 10%): Contact dermatitis, dry skin, sweating, eczema, pruritus, Uncommon (0.1% to 1%): Acne, alopecia, hirsutism, maculopapular rash, skin discoloration, urticaria, ecchymosis, leukopenia, Rare (less than 0.1%): Angioedema, erythema, exfoliative dermatitis, fungal dermatitis, herpes zoster, leukoderma, multiforme erythema, petechial rash, pustular rash, Stevens-Johnson syndrome, vesiculobullous rash, anemia, eosinophilia, fibrin decrease, fibrinogen decrease, iron deficiency anemia, leukocytosis, lymphocytosis, macrocytic anemia, thrombocytopenia[Ref], Common (1% to 10%): Dysmenorrhea, vaginitis, amenorrhea, libido increase, urinary tract infection (both male and female), urinary frequency, Uncommon (0.1% to 1%): Libido decreased, abnormal ejaculation, hematuria, impotence, menorrhagia, polyuria, urinary incontinence, Rare (less than 0.1%): Anorgasmia, breast abscess, breast neoplasm, creatinine increase, cystitis, dysuria, epididymitis, female lactation, nocturia, urinary retention, urinary urgency[Ref], Very common (10% or more): Fever (15%), accidental injury (14%), Uncommon (0.1% to 1%): Ear pain, taste perversion, tinnitus, Rare (less than 0.1%): Alcohol intolerance, deafness, taste loss, parosmia, taste loss[Ref], Common (1% to 10%): Weight decrease, weight gain, peripheral edema, facial edema, Rare (less than 0.1%): Bilirubinemia, general edema, gamma glutamyl transpeptidase increase, hyperglycemia[Ref], Common (1% to 10%): Neck pain, arthralgia, myalgia, decreased reflexes, back pain, increased reflexes, asthenia, Uncommon (0.1% to 1%): Arthritis, leg cramps, myasthenia, twitching, Rare (less than 0.1%): Bursitis, muscle atrophy, pathological fracture, tendinous contracture, Postmarketing reports: Rhabdomyolysis (among patients experiencing hypersensitivity reactions)[Ref], Uncommon (0.1% to 1%): Flushing, hot flashes, hypertension, palpitations, postural hypotension, syncope, tachycardia, vasodilation[Ref], Postmarketing reports: Agranulocytosis, hemolytic anemia, lymphadenopathy not associated with hypersensitivity disorder[Ref], Uncommon (0.1% to 1%): Liver function tests abnormal, aspartate transaminase (AST) increased, Rare (less than 0.1%): Hepatitis, alanine transaminase ALT) increased, acute kidney failure, kidney failure, kidney pain[Ref]. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Reassuring News for Women Taking Epilepsy Meds While Pregnant. Pharmacotherapy 19 (1999): 877-80, 17. Side Effects What are the side effects of Lamictal (Lamotrigine)?. Re: Sexual side effects with lamictal Submitted by beatrice on Fri, 2008-03-28 19:55 I can't help you with this but my husband wants to know where he can get some of this Lamictal. This site complies with the HONcode standard for trustworthy health information: verify here. Clinical trials show that sudden Lamictal discontinuation may cause In worldwide postmarketing experience, rash-related death has been reported, but the numbers are too few to permit a precise estimate of rate. In adult patients (n=3348), serious rash associated with hospitalization and discontinuation was reported in 0.3% of patients in premarketing epilepsy trials. I've been on Lamictal since I was 20 and am taking 700mg a day. The Dangerous Side Effects of Lamictal [Ref], Postmarketing reports: Progressive immunosuppression, Lupus-like reaction, vasculitis, drug reaction with eosinophilia and systemic symptoms (DRESS), hemophagocytic lymphohistiocytosis (HLH)[Ref], Uncommon (0.1% to 1%): Allergic reaction, chills, malaise[Ref], Very common (10% or more): Dizziness (38%), headache (29%), ataxia (22%), somnolence (14%), Common (1% to 10%): Seizure exacerbation, incoordination, insomnia, tremor, speech disorder, amnesia, hypoesthesia, pain, gait abnormality, vertigo, dyspraxia, confusion, paresthesia, Uncommon (0.1% to 1%): Akathisia, aphasia, central nervous system depression, dysarthria, dyskinesia, hyperkinesia, hypertonia, movement disorder, myoclonus, sudden unexplained death in Epilepsy (SUDEP), Rare (less than 0.1%): Choreoathetosis, dystonia, extrapyramidal syndrome, faintness, grand mal seizures, hemiplegia, hyperalgesia, hyperesthesia, hypokinesia, hypotonia, neuralgia, muscle spasm, neuralgia, paralysis, peripheral neuritis, Very rare (less than 0.01%): Muscle spasm, paralysis, peripheral neuritis, Postmarketing reports: Exacerbation of Parkinsonian symptoms in patients with pre-existing Parkinson's disease, tics[Ref], Sudden unexplained death in epilepsy (SUDEP) was reported in 20 of 4700 patients with epilepsy during premarketing development. The possible effects of lamotrigine in a nursing newborn are not clearly known, but no side effects have been reported in most infants. Along with its needed effects, a medicine may cause some unwanted effects. Common side effects of Lamictal include: ataxia, skin rash, headache, insomnia, and nausea. Fadul CE, Meyer LP, Jobst BC, Cornell CJ, Lewis LD "Agranulocytosis Associated with Lamotrigine in a Patient with Low-grade Glioma." Desarkar P, Sinha VK "Lamotrigine-induced severe manic switch." Pharmacotherapy 18 (1998): 392-8, 8. FDA. However, it has some side effects (insomnia, nausea, mild constipation and pains on my sides) which are all gradually fading away. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Does Lamictal interact with other medications? [Ref], Common (1% to 10%): Depression, anxiety, irritability, disturbance of concentration, emotional lability, abnormal thinking, nervousness, Uncommon (0.1% to 1%): Apathy, euphoria, hallucinations, hostility, depersonalization, memory decrease, mind racing, panic attack, paranoid reaction, personality disorder, psychosis, sleep disorder, stupor, suicidal ideation, Rare (less than 0.1%): Delirium, delusions, dysphoria, manic depression reaction, neurosis, Postmarketing reports: Aggression, nightmares[Ref], Antiepileptic drugs (AEDs) increase the risk of suicidal thoughts or behavior.

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